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pentobarbital will minimize the level or outcome of netupitant/palonosetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Netupitant is mainly metabolized by CYP3A4; prevent use in individuals who will be chronically utilizing a robust CYP3A4 inducerWarning is warranted for people with renal and he